Go Back   Hardware Canucks > HARDWARE CANUCKS COMMUNITY > HardwareCanucks F@H Team

    
Reply
 
LinkBack Thread Tools Display Modes
  #1 (permalink)  
Old August 6, 2011, 09:52 PM
LCB001's Avatar
Folding Captain
 
Join Date: Feb 2008
Location: Aylmer QC.
Posts: 1,774

My System Specs

Default F@H Results Page Updated - New Key Result On Alzheimers Published

Stanford has updated their results page on the Folding@Home website, now listing 95 papers that have directly resulted from Folding.

Prof. Pande seems particularly excited about the latest work on Alzheimers.

From his blog;

Quote:
We have made a major update to the Results pageon the Folding@home web site. We now list 95 papers that have directly resulted from Folding@home, although we note that there are 193 papers from the Pande group in general. There are many new results to talk about, but I will just highlight a few below.
One major result is in the area of Alzheimer's Disease (paper #95). It is believed that Alzheimer's Disease results from the misfolding of the Abeta peptide. Understanding how Abeta misfolds could give us some key insights into how to cure Alzheimer's Disease. This paper experimentally tests a key prediction made in an earlier paper (paper #58: "Simulating oligomerization at experimental concentrations and long timescales: A Markov state model approach" by Nicholas W. Kelley, V. Vishal, Grant A. Krafft, and Vijay S. Pande. J. Chem. Phys. 129, 214707 (2008); DOI:10.1063/1.3010881). In this paper, we show experimentally that there appears to be a beta turn in the Abeta as predicted. This leads to a very stable form of misfolded Abeta which could be used as a starting point for a new Alzheimer's therapy. We are heavily pursuing this research direction at the moment.
Another key result is in the area of methods (paper #93). We are constantly honing our methods to improve Folding@home's ability to predict the behavior of proteins. This paper demonstrates the current state of the art in terms of both sampling and analysis. When compared to detailed TTET experiments, we show that our methods can piece out even fairly detailed aspects of folding. However, we also see the ways in which our models are not perfect, suggesting how we can improve our methods even further.
We'll highlight other papers as time goes on. I'm particuarly excited about these results. In particular, the results from paper #95 were first discovered several years ago, but we carried out several followup studies to verify them, etc. As always, I'm most excited about what we're doing now and hope to get some of our current key results in theses areas out from peer review soon.


This is why we Fold...

__________________
Folding For Team 54196

Reply With Quote
  #2 (permalink)  
Old August 6, 2011, 10:02 PM
Xeven's Avatar
MVP
F@H
 
Join Date: Aug 2010
Location: Vancouver, BC
Posts: 483
Default

Fold on!
__________________

PSXeven. Batards of the World Unite!
The gap between happiness and utter misery is only but a few inches
Reply With Quote
  #3 (permalink)  
Old August 6, 2011, 11:41 PM
Banned
F@H
 
Join Date: Aug 2007
Location: mtl
Posts: 12,694
Default

yhaa!!!

might not cure ya granpa today,but could cure him in a while,if he's still kicking then!!!
Reply With Quote
  #4 (permalink)  
Old August 7, 2011, 06:05 AM
PerryC's Avatar
Allstar
F@H
 
Join Date: Apr 2011
Location: Burton, NB
Posts: 737

My System Specs

Default

Quote:
Originally Posted by LCB001 View Post

This is why we Fold...


Most definitely....keep it up folders
__________________
The oath to serve your country did not include a contract for normal luxury, and comforts enjoyed within our society. On the contrary it implies hardships, loyalty and devotion to duty, regardless of rank
Reply With Quote
  #5 (permalink)  
Old August 7, 2011, 08:22 AM
stoanee's Avatar
Hall Of Fame
F@H
 
Join Date: Jun 2007
Location: Lacombe Alberta
Posts: 3,249

My System Specs

Default

Carry on the good work folders, I am excited to see results from the research.
__________________
heatware
Reply With Quote
Reply


Thread Tools
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
Innovation Cooling 7 Carat Diamond TIM Test results thread *NOW ACCEPTING RESULTS!!* Nademon Overclocking, Tweaking and Benchmarking 254 December 14, 2011 08:18 PM
New Research Paper Published Using -bigadv Results LCB001 HardwareCanucks F@H Team 2 June 29, 2010 04:54 PM
Why F@H; Alzheimer's Simulation work published LCB001 HardwareCanucks F@H Team 13 December 19, 2008 08:21 PM
1st Benchmark Result icodeit Overclocking, Tweaking and Benchmarking 6 November 23, 2008 06:02 AM
Published Unklmo Off Topic 11 February 28, 2008 03:03 PM