I got a Zune 80 on Canada's release day after 5 years of using the iPod. Really, both of the players do their job. As enaberif said, you will be required to use their own special software, so you cannot simply drag and drop. Compared with an iPod Classic 160GB, I found that the Zune did better at everything over the iPod. The only thing that I didnt like is the lack of an EQ, but the stock sound is awesome, so really, I shouldn't complain on this point.
Zune has a larger screen, so naturally, its better at watching movies and pictures than the iPod. But still, its painful watching a movie on a screen that small.
Zune software's interface is awesome, miles more attractive and interactive than iTunes, but IMO, iTunes was better at organizing music at a much larger scale, of course you will get used to whichever program you use.
The quality of the stock earphones of the Zune is better than the iPod, and looks durable (It is an IEM). It sounds all that great IMO, but sounds much better than the iPod stock headphones.
Zune has a radio, its just perfect! Only FM, wish it had AM, but at least it has a radio, im not complaining.
The fact that Zune 3.0 was merely a firmware update just made me love Zune alot more, I was really glad that all the old zune owners didnt get left in the dust, I got all the features of the new Zune, how fantastic is that!? iPod will have this feature eventually, but great job on Zune for adding this. Hopefully Zune 4.0 also is a firmware update
