The driver issuse have been sorted out for Vista X64.
WHat you may want to consider though is the PRelude will definatley have higher quality DAC's then what is present in the decoder of those headphones. -So using optical to those headphones would actually be a downgrade from straight analog.
People have been finding this even with A/V receivers and the Prelude. The DAC's are high quality.....
Not to mention the PRelude has one of the best heapdhones routines for gaming avialable that provides virtual surround sound.
Hope this helps.
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