Hmm, I'm actually a small handed person, so something like my previous MX518 was like holding a bowling ball with a scroll wheel. It's difficult for me to guess since the thing is so bloody ergonomic I can't really imagine someone not having it comfortably work for them. Altogether though the mouse is quite nice, button layout is great for both LH or RH, and the backlighting on the wheel/logo is subtle, not the slap you in the face turn it off kind of brightness.
__________________ Asus P5Q Pro | Q6600 - 3.6GHz @ 1.51 | Fuzion V2 - MCP655 - MCR220 | 2x2GB G.Skill Pi PC2-8500
Radeon HD 4850 | 2 x 150GB Raptor X - 250GB WD Caviar SE16 (Backup) | Corsair TX650 | Coolermaster HAF932
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