I have a feeling it is a power supply issue. While the Modu82+ is a very good unit, the rails may not be optimally set up for running such a high-powered card. We have to remember that the HD4870X2 goes into full 3D mode before any drivers are installed and to be honest with you, it sounds like you may be tripping the OCP. But then again, the automatic reboot has me scratching my head.
I would recommend you set your system to stock values and see if it will boot up then.
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