you can really do whatever you want.... I have my case setup so that ive got 2 intake fans on the front (1 &2) pulling air through my rad, blowing onto the GPU, and exhausting out 4 & 3 (a 120mm on 4 and 2x 140mm on 3)
If you wanted for dust, you could make all fans push air out of the case, and make the #4 draw air in, since its high up, but dont makee#3 intake, as dust would settle and menace you forever lol.
It also depends if you are using an ALC or not....If you are using an air cooler, this is the best setup IMHO, the picture above.
If youve got an ALC, or custom loop, you dont need much air blowing over the top of things, so dont worry too much
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Bought Items:
GTX 470 from ZeroFlux
Swiftech MCW60 from chubaka
Sold Items:
Steelseries Siberia V2 to MAK
Zalman Fan Controller, OCZ Mem Fan Funguseater
Current system:
i5 2500k @ 5 Ghz
Zotac gtx 470
8GB Corsair Dominator ram @ 1333
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