I have a 2008 pre-unibody Macbook pro (Core2Duo, 4GB ram), upgraded almost right away. I did an update at first, not a clean install. The experience was not that great, Mail kept randomly crashing and the whole thing would freeze up every so often.
It was so annoying I was ready to put 10.6 back on it. Instead I recorded the Lion image onto a USB stick, reformatted the hard drive, installed a clean copy of Lion and then restored my stuff from time machine. No more random crashes of apps and no freezes. What they did to spaces is a step back, but overall I think it's a net gain.
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