I don't think anyone runs non-amplified speakers from sound cards.
The setup would go like this instead:
Sound card -- (analog or digital) --> Receiver w/Amp -> Speakers/Monitors
or
Sound card -- (analog or digital) --> Receiver -> Pre-amp -> Speakers/Monitors
and at that point you could, as argued in this thread, just go with onboard and SPDIF to the receiver.
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