Honestly, I ran a 4.0GHz i7 and a GTX280 for quite some time on an MCR220 and low-speed fans. Temps weren't legendary, but it was plenty. Just a CPU won't be an issue at all. Depending on the GPU, you may win up needing either more rad or stronger fans later on, though.
__________________ i7 2600K | ASUS Maximus IV GENE-Z | GTX Titan | Corsair DDR3-2133
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