The gigabyte P45-DS3L P45 and the asus P5Q SE P45 vary in the little details. The biggest differences I notice are gigabytes "ultra durable" and the audio chip set. Basically a price or preference choice. If you have a preference for one brand and there isn't a big difference in price go with your preference. If the price difference is big enough and you don't have a preference go for the cheaper one.
__________________ Q6600 3.0GHZ (9x333) stockV | ATI 5850 | OCZ Platinum 4GB PC2-6400 DDR2 5.4.4.15 1.9V | Silverstone Raven RV01 | Gigabyte EP45-DS3R
Corsair Professional HX750W | Windows 7 | Crossbow mounted Xigmatek HDT-S1283 | LG W2242TQ-BF 22" | Samsung 2253BW 22" |